CERF Complex: Regulation of Cell Division and Growth (P22064)

Target Name: CECR2-containing remodeling factor complex

NCBI ID: P22064

CECR2-containing remodeling factor complex

Other Name(s): CERF complex

CERF Complex: Regulation of Cell Division and Growth

The CECR2-containing remodeling factor complex (CERF complex) is a protein that plays a crucial role in the regulation of cell division and growth. It is a complex of proteins that work together to ensure the proper execution of cell division and the regulation of cell growth. The CERF complex is made up of several different proteins, including CECR2, which is the protein that is of interest in this article.

CECR2 is a protein that is known to function as a negative regulator of cell division. It works by preventing the G1 phase of cell division from transitioning into the S phase. This is important because during the S phase, the cell prepares for cell division by producing more DNA. By preventing the G1 phase from transitioning into the S phase, CECR2 ensures that the cell does not have enough time to prepare for cell division, which can lead to the development of cancer.

The CERF complex also includes several other proteins that work together to ensure the proper execution of cell division and the regulation of cell growth. These proteins include the transcription factor p21, which plays a role in the regulation of cell growth and the apoptosis protein p53, which is responsible for ensuring the regulation of cell growth and the apoptosis of damaged cells.

One of the challenges in the study of the CERF complex is the difficulty in purifying and reconstituting the complex. This is because the complex is made up of many different proteins, and it can be difficult to isolate and reconstitute each of these proteins in a purified format. However, recent advances in technology have allowed researchers to study the CERF complex more fully and to understand its role in cell division and growth.

In addition to its role in the regulation of cell division and growth, the CERF complex is also of interest as a potential drug target or biomarker. The CERF complex is thought to be involved in the regulation of cell cycle progression, which is important for the development and progression of many types of cancer. Therefore, targeting the CERF complex with drugs or other therapeutic agents may be a promising strategy for the treatment of cancer.

Another potential use of the CERF complex is as a biomarker for the diagnosis and prognosis of cancer. The CERF complex is expressed in many different types of cancer, including breast cancer, lung cancer, and colorectal cancer. Therefore, measuring the expression of the CERF complex in cancer cells or in tissue samples from cancer patients may be a useful diagnostic or prognostic tool.

In conclusion, the CECR2-containing remodeling factor complex is a protein that plays a crucial role in the regulation of cell division and growth. It is made up of several different proteins, including CECR2, which is a negative regulator of cell division. The CERF complex is also of interest as a potential drug target or biomarker for the treatment of cancer. Further research is needed to fully understand the role of the CERF complex in cell division and growth, as well as its potential as a drug target or biomarker.

Protein Name: CECR2-containing Remodeling Factor Complex

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•   expression level;
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